Article
Pseudomonas aeruginosa AlgR represses the Rhl quorum-sensing system in a biofilm-specific manner.
Journal of bacteriology - 1 Nov 2007
Morici Lisa A, Carterson Alexander J, Wagner Victoria E, Frisk Anders, Schurr Jill R, Höner zu Bentrup Kerstin, Hassett Daniel J, Iglewski Barbara H, Sauer Karin, Schurr Michael J
Abstract excerpt
AlgR controls numerous virulence factors in Pseudomonas aeruginosa, including alginate, hydrogen cyanide production, and type IV pilus-mediated twitching motility. In this study, the role of AlgR in biofilms was examined in continuous-flow and static biofilm assays. Strain PSL317 (DeltaalgR) produced one-third the biofilm biomass of wild-type strain PAO1. Complementation with algR, but not fimTU-pilVWXY1Y2E,...
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