Article
Genotyping on a complementary metal oxide semiconductor silicon polymerase chain reaction chip with integrated DNA microarray.
Analytical chemistry - 1 Jul 2002
Trau Dieter, Lee Thomas M H, Lao Alex I K, Lenigk Ralf, Hsing I-Ming, Ip Nancy Y, Carles Maria C, Sucher Nikolaus J
Abstract excerpt
A novel method for the fast identification of genetic material utilizing a micro-DNA amplification and analysis device (micro-DAAD) consisting of multiple PCR microreactors with integrated DNA microarrays was developed. The device was fabricated in Si-technology and used for the genotyping of Chinese medicinal plants on the basis of differences in the noncoding region of the 5S-rRNA gene. Successful amplification...
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