Article
Development of a microelectronic chip array for high-throughput genotyping of Helicobacter species and screening for antimicrobial resistance.
Journal of biomolecular screening - 1 Apr 2005
Xing James Z, Clarke Chris, Zhu Lijun, Gabos Stephan
Abstract excerpt
A microelectronic array assay was developed to specifically genotype Helicobacter pylori versus Helicobacter heilmannii and to determine antimicrobial resistance. Helicobacter 16S rRNA and 23S rRNA genes were specifically generated with Helicobacter genus-specific primers, respectively. The single-nucleotide polymorphisms (SNPs) in 16S rRNA, 268T specific in the H. pylori sequence, and 263A specific in H....
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