Article
Single nucleotide polymorphism seeking long term association with complex disease.
Nucleic acids research - 1 Aug 2002
Kirk Brian W, Feinsod Matthew, Favis Reyna, Kliman Richard M, Barany Francis
Abstract excerpt
Successful investigation of common diseases requires advances in our understanding of the organization of the genome. Linkage disequilibrium provides a theoretical basis for performing candidate gene or whole-genome association studies to analyze complex disease. However, to constructively interrogate SNPs for these studies, technologies with sufficient throughput and sensitivity are required. A plethora of...
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