Article
Mapping genetic alterations in tumors with single nucleotide polymorphisms.
Current opinion in oncology - 1 Jan 2003
Zhou Wei
Abstract excerpt
Single nucleotide polymorphisms are the most abundant genetic markers in the human genome whose analyses can be easily conducted on a large scale. Most established methods for high-throughput single nucleotide polymorphism analyses are qualitative and are not suitable for genetic analysis of archived tumor specimens, which have compromised tissue integrity and normal tissue contaminations. Recent studies have...
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