Article
Association between polymorphisms in the GSTA4 gene and risk of lung cancer: a case-control study in a Southeastern Chinese population.
Molecular carcinogenesis - 1 Mar 2009
Qian Ji, Jing Jianying, Jin Guangfu, Wang Haifeng, Wang Yi, Liu Hongliang, Wang Haijian, Li Rui, Fan Weiwei, An Yu, Sun Weiwei, Wang Yi, Ma Hongxia, Miao Ruifeng, Hu Zhibin, Jin Li, Wei Qingyi, Shen Hongbing, Huang Wei, Lu Daru
Abstract excerpt
GST Alpha 4 (GSTA4) has an important role in the protection against oxidative stress induced by carcinogens such as tobacco smoke. However, few studies investigated the association between GSTA4 polymorphisms and lung cancer risk. We genotyped three selected GSTA4 SNPs (rs182623 - 1718:T > A, rs3798804 + 5034:G > A and rs316141 + 13984:C > T) in a case-control study of 500 lung cancer patients and 517 cancer-free...
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