Article
Involvement of replicative polymerases, Tel1p, Mec1p, Cdc13p, and the Ku complex in telomere-telomere recombination.
Molecular and cellular biology - 1 Aug 2002
Tsai Yun-Luen, Tseng Shun-Fu, Chang Shih-Husan, Lin Chuan-Chuan, Teng Shu-Chun
Abstract excerpt
Telomere maintenance is required for chromosome stability, and telomeres are typically replicated by the action of the reverse transcriptase telomerase. In both tumor and yeast cells that lack telomerase, telomeres are maintained by an alternative recombination mechanism. Genetic studies have led to the identification of DNA polymerases, cell cycle checkpoint proteins, and telomere binding proteins involved in...
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