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Article

The IIIc alternative of Fgfr2 is a positive regulator of bone formation.

Development (Cambridge, England) - 1 Aug 2002

Eswarakumar Vereragavan P, Monsonego-Ornan Efrat, Pines Mark, Antonopoulou Ileana, Morriss-Kay Gillian M, Lonai Peter

Abstract excerpt

Fibroblast growth factor receptor type 2 (FGFR2) plays major roles in development. Like FGFR1 and FGFR3, it exists as two splice variants, IIIb and IIIc. We have investigated in the mouse the function of FGFR2IIIc, the mesenchymal splice variant of FGFR2. Fgfr2IIIc is expressed in early mesenchymal condensates and in the periosteal collar around the cartilage models; later it is expressed in sites of both...

Read the complete abstract on PubMed

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 12135917
DOI: 10.1242/dev.129.16.3783

Genes

FGFR2
FGF18
FGFR1
FGFR3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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