Article
Label-free electrochemical hybridization genosensor for the detection of hepatitis B virus genotype on the development of Lamivudine resistance.
Analytical chemistry - 1 Aug 2005
Ariksoysal Dilsat Ozkan, Karadeniz Hakan, Erdem Arzum, Sengonul Aylin, Sayiner A Arzu, Ozsoz Mehmet
Abstract excerpt
The resistance analysis related to the hepatitis B virus (HBV) genotyping and treatment procured key information for the study of infected patients. The aim of this study was to develop a novel assay for the voltammetric detection of DNA sequences related to the HBV genotype on the development of lamuvidine resistance by monitoring the oxidation signal of guanine. This new technique not only provides a rapid,...
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