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Article

A role for the Cr2 gene in modifying autoantibody production in systemic lupus erythematosus.

Journal of immunology (Baltimore, Md. : 1950) - 1 Aug 2002

Wu Xiaobo, Jiang Ning, Deppong Christine, Singh Jasvinder, Dolecki Gregory, Mao Dailing, Morel Laurence, Molina Hector D

Abstract excerpt

Systemic lupus erythematosus is an autoimmune disease characterized by autoantibody production against nuclear Ags. Recent studies suggest that the Cr2 gene, which encodes for complement receptor (CR)1 and CR2, is important in disease susceptibility. Because the precise disease phenotype related to this gene, in isolation or in relation to other genetic loci, is not known, we analyzed C57BL/6 mice with a targeted...

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Source

Identifiers

PMID: 12133988
DOI: 10.4049/jimmunol.169.3.1587

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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