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Article

Molecular mechanisms underlying human synovial sarcoma development

1 Jan 2000

Abstract excerpt

Synovial sarcomas are rather common among soft-tissue tumors, occurring at any age but affecting mainly young adults. The vast majority of synovial sarcomas carries a t(X;18)(p11.2;q11.2) chromosomal translocation, in about one-third of the cases as the sole cytogenetic anomaly. Several studies have indicated that the t(X;18) translocation arises exclusively in synovial sarcomas, therefore being an excellent tool...

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PMID: 11107170
DOI: 10.1002/1098-2264(2000)9999:9999<::aid-gcc1056>3.0.co;2-g

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