Article
Complex genetics of obesity in mouse models.
Annual review of nutrition - 1 Jan 2008
Pomp Daniel, Nehrenberg Derrick, Estrada-Smith Daria
Abstract excerpt
Traits related to energy balance and obesity are exceptionally complex, with varying contributions of genetic susceptibility and interacting environmental factors. The use of mouse models has been a powerful driving force in understanding the genetic architecture of polygenic traits such as obesity. However, the use of mouse models for analysis of complex traits is at an important crossroad. Genome-wide...
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