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Article

P301L tauopathy: confocal immunofluorescence study of perinuclear aggregation of the mutated protein.

Journal of the neurological sciences - 15 Aug 2002

Adamec Emil, Murrell Jill R, Takao Masaki, Hobbs Wendy, Nixon Ralph A, Ghetti Bernardino, Vonsattel Jean P

Abstract excerpt

The clinical and neuropathological features in the P301L tauopathy have been described in several kindreds. In this study, we present findings in two previously unreported patients, evaluated both genetically, neuropathologically, and with multiparametric confocal immunofluorescence. The patients were female, with age 65 and 75 years old, respectively. Both exhibited clinical symptoms of frontotemporal dementia...

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Identifiers

PMID: 12127682
DOI: 10.1016/s0022-510x(02)00150-8

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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