Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Hereditary Pick's disease with the G272V tau mutation shows predominant three-repeat tau pathology.

Brain : a journal of neurology - 1 Nov 2005

Bronner I F, ter Meulen B C, Azmani A, Severijnen L A, Willemsen R, Kamphorst W, Ravid R, Heutink P, van Swieten J C

Abstract excerpt

Frontotemporal dementia and parkinsonism linked to chromosome 17 have been associated with mutations in the microtubule associated protein tau (MAPT or tau) gene. This disorder is characterized by a large spectrum of neuronal and glial tau lesions in different brain regions. Pick bodies were foun...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Blotting, Western
Share to Chromosomes, Human, Pair 17
Share to DNA Mutational Analysis

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Frontal Lobe

Share to Haplotypes

Share to Nerve Tissue Proteins

Share to Pick Disease of the Brain

Share to tau Proteins

Source

Identifiers

PMID: 16014652
DOI: 10.1093/brain/awh591

Genes

MAPT

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-16014652-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Hereditary Pick's disease with the G272V tau mutation shows predominant three-repeat tau pathology.PMID 16014652Read ↗

Tau gene mutation G389R causes a tauopathy with abundant pick body-like inclusions and axonal deposits.Semantic proximity Read ↗

The L266V tau mutation is associated with frontotemporal dementia and Pick-like 3R and 4R tauopathy.Semantic proximity Read ↗

<i>Tau</i>Gene Mutation K257T Causes a Tauopathy Similar to Pick's DiseaseSemantic proximity Read ↗

Frontotemporal dementia with Pick‐type histology associated with Q336R mutation in the tau geneSemantic proximity Read ↗

Progress in hereditary tauopathies: a mutation in the Tau gene (G389R) causes a Pick disease-like syndrome.Semantic proximity Read ↗

Pick's disease associated with the novel <i>Tau</i> gene mutation K369ISemantic proximity Read ↗

From genotype to phenotype: a clinical pathological, and biochemical investigation of frontotemporal dementia and parkinsonism (FTDP-17) caused by the P301L tau mutation.Semantic proximity Read ↗

Variable phenotypic expression and extensive tau pathology in two families with the novel tau mutation L315R.Semantic proximity Read ↗

A Novel Tau Mutation in Exon 12, p.Q336H, Causes Hereditary Pick Disease.Semantic proximity Read ↗

Invited review: Neuropathology of tauopathies: principles and practice.Semantic proximity Read ↗

Pick's disease pathology of a missense mutation of S305N of frontotemporal dementia and parkinsonism linked to chromosome 17: another phenotype of S305N.Semantic proximity Read ↗

Deep clinical and neuropathological phenotyping of Pick disease.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.