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Article

Sharing of polyglutamine localization by the neuronal nucleus and cytoplasm in CAG-repeat diseases.

Neuropathology and applied neurobiology - 1 Dec 2004

Yamada M, Tan C-F, Inenaga C, Tsuji S, Takahashi H

Abstract excerpt

The expansion of a trinucleotide cytosine adenine and guanine (CAG) repeat that codes for polyglutamine is a common gene mutation in the family of hereditary neurodegenerative diseases that includes Machado-Joseph disease (MJD) and dentatorubral-pallidoluysian atrophy (DRPLA). The presence of ubiquitinated neuronal intranuclear inclusions (NIIs) has been recognized as a neuropathological hallmark of these...

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Identifiers

PMID: 15541006
DOI: 10.1111/j.1365-2990.2004.00583.x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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