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Article

Tauopathy with hippocampal 4-repeat tau immunoreactive spherical inclusions: a report of three cases.

Brain pathology (Zurich, Switzerland) - 1 Mar 2018

Kovacs Gabor G, Kwong Linda K, Grossman Murray, Irwin David J, Lee Edward B, Robinson John L, Suh Eunran, Van Deerlin Vivianna M, Lee Virginia M, Trojanowski John Q

Abstract excerpt

Tauopathies are a major group of neurodegenerative proteinopathies characterized by the accumulation of abnormal and hyperphosphorylated tau proteins in the brain. Tau pathology is characterized as 3R (repeat) or 4R predominant or mixed 3R and 4R type. Here we report three cases lacking mutations in the microtubule associated protein tau (MAPT) gene with unusual tau pathology. The age at onset and duration of...

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Identifiers

PMID: 28019685
DOI: 10.1111/bpa.12482
PMCID: PMC5484758

Genes

MAPT

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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