Article
[BRCA2 gene mutation detection in hereditary ovarian cancer tissues].
Zhonghua fu chan ke za zhi - 18 Jun 2002
Qiao Yuhuan, Chen Ping, Shi Huirong, Zhao Guoqiang, Wu Dan
Abstract excerpt
OBJECTIVE: The aim of this study was to detect the mutation of BRCA2 gene in hereditary ovarian cancer tissues to probe the clinical significance of it. METHODS: DNA was abstract from paraffin embedded tissues archived in pathology department. A pair of primer located on 11 exon was used to detect the 6174 delT mutation,BRCA2 gene mutation in 12 hereditary ovarian cancer patients and 15 sporadic ovarian cancer...
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