Article
[Hereditary ovarian cancer. The role of BRCA1 gene dysfunction in response to chemotherapy].
Ginekologia polska - 1 Mar 2011
Blecharz Paweł, Karolewski Kazimierz, Urbański Krzysztof
Abstract excerpt
Hereditary ovarian cancer is often believed to be as a distinct disease. It is diagnosed earlier than its sporadic type; serous subtypes and more advanced stages are usually observed. Mutations of genes like BRCA1, BRCA2, MMR (MLH1, MSH2, PMS1, PMS2) are strictly associated with the heredity of ovarian and also breast cancer. Systematic controls and specific procedures to lower the risk of those tumors are...
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