Article
ACE gene polymorphism and disease progression of IgA nephropathy in Asians in Singapore.
Nephron - 1 Jul 2002
Lau Y K, Woo K T, Choong H L, Zhao Y, Tan H B, Cheung W, Yap H K
Abstract excerpt
The deletion polymorphism of the angiotensin-converting enzyme (ACE) gene has been considered as a risk factor for IgA nephropathy and for its progression to end-stage renal failure. However, results from various studies are conflicting. We had genotyped the ACE gene in 100 patients with IgA nephropathy, 32 of whom were in end-stage renal failure and in 90 normal adult subjects. All DD cases were subjected to...
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