Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Cause of Familial and Multiple Gastrointestinal Autonomic Nerve Tumors With Hyperplasia of Interstitial Cells of Cajal Is Germline Mutation of the c-kit Gene

1 Feb 2000

Abstract excerpt

Hirota, Seiichi M.D.; Okazaki, Toshihiko M.D.; Kitamura, Yukihiko M.D.; O'Brien, Paul M.B., F.R.C.P.C.; Kapusta, Linda M.D., F.R.C.P.C.; Dardick, Irving M.D., F.R.C.P.C. Author Information

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Gastrointestinal Tumor Research and Treatment
Share to Neuroendocrine Tumor Research Advances
Share to Neurofibromatosis and Schwannoma Cases

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 10680913
DOI: 10.1097/00000478-200002000-00045

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Cause of Familial and Multiple Gastrointestinal Autonomic Nerve Tumors With Hyperplasia of Interstitial Cells of Cajal Is Germline Mutation of the c-kit GenePMID 10680913Read ↗

Mesenchymal tumors of the gastrointestinal tract: a paradise for acronyms (STUMP, GIST, GANT, and now GIPACT), implication of c-kit in genesis, and yet another of the many emerging roles of the interstitial cell of Cajal in the pathogenesis of gastrointestinal diseases?Semantic proximity Read ↗

Interstitial cells of Cajal in health and disease. Part I: Normal ICC structure and function with associated motility disordersSemantic proximity Read ↗

A loss-of-function mutation of c-kit results in depletion of mast cells and interstitial cells of Cajal, while its gain-of-function mutation results in their oncogenesis.Semantic proximity Read ↗

Therapy-refractory gastrointestinal motility disorder in a child with c-kit mutations.Semantic proximity Read ↗

Adrenal Ganglioneuromas in Children with Multiple Endocrine Neoplasia Type 2: A Report of Two CasesSemantic proximity Read ↗

Familial gastrointestinal stromal tumors associated with dysphagia and novel type germline mutation of KIT geneSemantic proximity Read ↗

A comprehensive analysis of the clinical characteristics and laboratory features in 179 patients with autoimmune autonomic ganglionopathy.Semantic proximity Read ↗

Triple A Syndrome Beyond the Classic Triad: Progression to Refractory Multisegmental Gastrointestinal DysmotilitySemantic proximity Read ↗

Gastrointestinal: Pancreatic NETs with GCGR heterozygous mutation: Mahvash disease.Semantic proximity Read ↗

Gastrointestinal pacemaker cell tumor (GIPACT): gastrointestinal stromal tumors show phenotypic characteristics of the interstitial cells of Cajal.Semantic proximity Read ↗

Polyclonal nature of diffuse proliferation of interstitial cells of Cajal in patients with familial and multiple gastrointestinal stromal tumoursSemantic proximity Read ↗

Pediatric disorders with autonomic dysfunction: what role for PHOX2B?Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.