Article
Elbow and Noc define a family of zinc finger proteins controlling morphogenesis of specific tracheal branches.
Development (Cambridge, England) - 1 Aug 2002
Dorfman Ruslan, Glazer Lillian, Weihe Ulrich, Wernet Mathias F, Shilo Ben-Zion
Abstract excerpt
The elbow (elB) gene encodes a conserved nuclear protein with a single zinc finger. Expression of ElB is restricted to a specific subset of tracheal cells, namely the dorsal branch and the lateral trunks. Stalled or aberrant migration of these branches is observed in elB mutant embryos. Conversely, ElB misexpression in the trachea gave rise to absence of the visceral branch and an increase in the number of cells...
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