Article
Structural predictions for the central domain of dystrophin.
FEBS letters - 12 Mar 1990
Cross R A, Stewart M, Kendrick-Jones J
Abstract excerpt
The amino acid sequence of dystrophin indicates that the molecule has globular N- and C-terminal domains separated by a long central rod domain. The central rod contains multiple repeats, about 100 amino acids long and of variable length. These diverge sufficiently in sequence that, in previous studies, only 14 of the most similar repeats have been aligned and analysed in any detail. We show here that a heptad...
Topics
- Actinin
- Amino Acid Sequence
- Dystrophin
- Models, Structural
- Molecular Sequence Data
- Muscle Proteins
- Mutation
- Protein Conformation
- Spectrin