Article
Phenotypic characteristics of the nucleus pulposus: expression of hypoxia inducing factor-1, glucose transporter-1 and MMP-2.
Cell and tissue research - 1 Jun 2002
Rajpurohit Ramesh, Risbud Makarand V, Ducheyne Paul, Vresilovic Edward J, Shapiro Irving M
Abstract excerpt
Attempts to study the biology of the nucleus pulposus have been limited in scope due to the low rates of cell proliferation, difficulties in maintaining viable disc cells in culture and the absence of a clearly defined phenotype. The major objective of this communication is to construct a phenotypic signature for cells of the nucleus pulposus that is based on the hypothesis that in response to restriction on...
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