Article
A polymorphism of the 5'-flanking region of the glucocorticoid receptor gene locus is associated with basal cortisol secretion in men.
Metabolism: clinical and experimental - 1 Sept 2000
Rosmond R, Chagnon Y C, Chagnon M, Pérusse L, Bouchard C, Björntorp P
Abstract excerpt
There is growing evidence that cortisol secretion and/or metabolism is associated with cardiovascular risk factors. Previous studies have shown that cardiovascular risk factors are associated with stimulated cortisol secretion and not with basal cortisol secretion. With the restriction enzyme Tth111I, a variant of the 5'-flanking region of the glucocorticoid receptor gene locus (GRL) was identified. The genotypes...
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