Article
Interleukin-10 promoter polymorphism in multiple sclerosis: association with disease progression.
European cytokine network - 1 Jan 2000
Almeras Lionel, Meresse Bertrand, Seze Jérôme, De Lefranc D, Dubucquoi Sylvain, Fajardy Isabelle, Vermersch Patrick, Prin Lionel
Abstract excerpt
Interleukin-10 (IL-10) is a potent anti-inflammatory and immunosuppressive cytokine that modulates disease expression in multiple sclerosis (MS) and experimental autoimmune encephalomyelitis (EAE). In previous studies, two dinucleotide repeat elements (microsatellites G and R) were identified, re...
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