Article
IL-4 dependent alternatively-activated macrophages have a distinctive in vivo gene expression phenotype.
BMC immunology - 4 Jul 2002
Loke P'ng, Nair Meera G, Parkinson John, Guiliano David, Blaxter Mark, Allen Judith E
Abstract excerpt
BACKGROUND: "Alternatively-activated" macrophages are found in Th2-mediated inflammatory settings such as nematode infection and allergic pulmonary inflammation. Due in part to a lack of markers, these cells have not been well characterized in vivo and their function remains unknown. RESULTS: We have used murine macrophages elicited by nematode infection (NeM(phi)) as a source of in vivo derived alternatively...
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