Article
A novel link between the proteasome pathway and the signal transduction pathway of the bone morphogenetic proteins (BMPs).
BMC cell biology - 21 Jun 2002
Lin Yin, Martin Jennifer, Gruendler Cornelia, Farley Jennifer, Meng Xianwang, Li Bi-Yu, Lechleider Robert, Huff Carla, Kim Richard H, Grasser William A, Paralkar Vishwas, Wang Tongwen
Abstract excerpt
BACKGROUND: The intracellular signaling events of the bone morphogenetic proteins (BMPs) involve the R-Smad family members Smad1, Smad5, Smad8 and the Co-Smad, Smad4. Smads are currently considered to be DNA-binding transcriptional modulators and shown to recruit the master transcriptional co-act...
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