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Article

Frequent mutations of Fas gene in nasal NK/T cell lymphoma.

Oncogene - 11 Jul 2002

Takakuwa Tetsuya, Dong Zhiming, Nakatsuka Shinichi, Kojya Shizuo, Harabuchi Yasuaki, Yang Woo-Ick, Nagata Shigekazu, Aozasa Katsuyuki

Abstract excerpt

Fas (Apo-1/CD95) is a cell-surface receptor involved in cell death signaling through binding of Fas ligand. Mutation of Fas gene in lymphoid cells results in accumulation of these cells, which might thus contribute to lymphomagenesis. We examined the open reading frame of Fas cDNA in 14 cases of nasal NK/T-cell lymphoma. Mutations of Fas gene were detected in seven (50%) of 14 cases which comprised four...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 12096347
DOI: 10.1038/sj.onc.1205571

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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