Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Immortalization of Normal Adult Human Middle Ear Epithelial Cells Using a Retrovirus Containing the E6/E7 Genes of Human Papillomavirus Type 16

1 Jun 2002

Abstract excerpt

A human middle ear epithelial cell line (HMEEC-1) was established using human papillomavirus E6/E7 genes. HMEEC-1 has remained morphologically and phenotypically stable, even after 50 passages. The cells are anchorage-dependent and nontumorigenic when injected into nude mice. This cell line thus provides a new tool for the study of normal cell biology and the pathological processes associated with the epithelial...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Ear and Head Tumors
Share to Ear Surgery and Otitis Media
Share to Herpesvirus Infections and Treatments

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 12090706
DOI: 10.1177/000348940211100606

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Immortalization of Normal Adult Human Middle Ear Epithelial Cells Using a Retrovirus Containing the E6/E7 Genes of Human Papillomavirus Type 16PMID 12090706Read ↗

Immortalization without neoplastic transformation of human mesenchymal stem cells by transduction with HPV16 E6/E7 genes.Semantic proximity Read ↗

Characterization of Human Bronchial Epithelial Cells Immortalized by the E6 and E7 Genes of Human Papillomavirus Type 16Semantic proximity Read ↗

Establishment and characterization of an immortalized human sebaceous gland cell line (SZ95).Semantic proximity Read ↗

Immortalization of distinct human mammary epithelial cell types by human papilloma virus 16 E6 or E7.Semantic proximity Read ↗

The Role of Human Papillomavirus 16 E6 in Anchorage-Independent and Invasive Growth of Mouse Tonsil EpitheliumSemantic proximity Read ↗

Human epithelial cells immortalized by human papilloma viruses.Semantic proximity Read ↗

Mucin Gene Expression in Human Middle Ear EpitheliumSemantic proximity Read ↗

The E7 gene of human papillomavirus type 16 is sufficient for immortalization of human epithelial cellsSemantic proximity Read ↗

Establishment and characterization of an immortalized human oviductal cell line.Semantic proximity Read ↗

The E6 and E7 genes of human papillomavirus type 6 have weak immortalizing activity in human epithelial cellsSemantic proximity Read ↗

Immortalization and altered differentiation of human keratinocytes in vitro by the E6 and E7 open reading frames of human papillomavirus type 18Semantic proximity Read ↗

Culture, Immortalization, and Characterization of Human Meibomian Gland Epithelial CellsSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.