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Article

The Role of Human Papillomavirus 16 E6 in Anchorage-Independent and Invasive Growth of Mouse Tonsil Epithelium

1 May 2007

Abstract excerpt

OBJECTIVE: To provide a manipulatable system to study the mechanism of human papillomavirus 16 (HPV16) E6-related transformation of an epithelial cell type affected by HPV16 in humans. DESIGN: Biochemical and physiological studies of mouse tonsil epithelial cells (MTECs) transformed with HPV16 oncogenes plus H-ras in vitro and in vivo. SETTING: Basic research laboratory. PARTICIPANTS: C57BL/6 mice. INTERVENTIONS:...

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PMID: 17515506
DOI: 10.1001/archotol.133.5.495

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