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Article

Human leukocyte antigen class II alleles may contribute to the severity of hepatitis C virus-related liver disease.

The Journal of infectious diseases - 1 Jul 2002

Hüe Sophie, Cacoub Patrice, Renou Christophe, Halfon Philippe, Thibault Vincent, Charlotte Frédéric, Picon Magali, Rifflet Hervé, Piette Jean Charles, Pol Stanislas, Caillat-Zucman Sophie

Abstract excerpt

Whether the host's immune response genes influence the severity of hepatitis C virus (HCV) liver disease is controversial. Human leukocyte antigen (HLA) class II alleles were analyzed in 233 HCV RNA-positive patients with chronic active hepatitis (197 patients with Knodell index of fibrosis F0-F3 and 36 patients with index of F4). The 2 groups did not differ by sex, duration of infection, mode of contamination,...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 12089669
DOI: 10.1086/341086

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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