Article
Effects of double-strand break repair proteins on vertebrate telomere structure.
Nucleic acids research - 1 Jul 2002
Wei Chao, Skopp Rose, Takata Minoru, Takeda Shunichi, Price Carolyn M
Abstract excerpt
Although telomeres are not recognized as double-strand breaks (DSBs), some DSB repair proteins are present at telomeres and are required for telomere maintenance. To learn more about the telomeric function of proteins from the homologous recombination (HR) and non-homologous end joining pathways (NHEJ), we have screened a panel of chicken DT40 knockout cell lines for changes in telomere structure. In contrast to...
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