Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Membrane-type matrix metalloproteinases mediate curcumin-induced cell migration in non-tumorigenic colon epithelial cells differing in Apc genotype.

Carcinogenesis - 1 Jun 2002

Fenton Jenifer I, Wolff Margaret S, Orth Michael W, Hord Norman G

Abstract excerpt

Colonic epithelial cell migration is required for normal differentiated cell function. This migratory phenotype is dependent upon wild-type adenomatous polyposis coli (Apc) expression. Non-tumorigenic murine colon epithelial cell lines with distinct Apc genotypes, i.e. young adult mouse colon (YAMC; Apc(+/+)) and immortomouse/Min colon epithelial (IMCE; Apc(Min/+) cells) were used to assess the association...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Curcumin
Share to Gelatinases
Share to Genes, APC

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Hepatocyte Growth Factor

Share to Hydroxamic Acids

Share to Matrix Metalloproteinase Inhibitors

Share to Matrix Metalloproteinases

Share to Protease Inhibitors

Source

Identifiers

PMID: 12082030
DOI: 10.1093/carcin/23.6.1065

Genes

HGF
EGF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Membrane-type matrix metalloproteinases mediate curcumin-induced cell migration in non-tumorigenic colon epithelial cells differing in Apc genotype.PMID 12082030Read ↗

Flavonoids promote cell migration in nontumorigenic colon epithelial cells differing in Apc genotype: implications of matrix metalloproteinase activity.Semantic proximity Read ↗

MMP12 knockout prevents weight and muscle loss in tumor-bearing mice.Semantic proximity Read ↗

The adenomatous polyposis coli tumor suppressor protein localizes to plasma membrane sites involved in active cell migration.Semantic proximity Read ↗

Genotype-phenotype correlation in murine Apc mutation: differences in enterocyte migration and response to sulindac.Semantic proximity Read ↗

ERK activation drives intestinal tumorigenesis in Apc(min/+) mice.Semantic proximity Read ↗

Induction of inflammatory bowel disease accelerates adenoma formation in Min +/- mice.Semantic proximity Read ↗

Forced expression of the tumor suppressor adenomatosis polyposis coli protein induces disordered cell migration in the intestinal epithelium.Semantic proximity Read ↗

The tumor suppressor Adenomatous polyposis coli regulates T lymphocyte migration. Insights from familial polyposis patientsSemantic proximity Read ↗

The tumor suppressor adenomatous polyposis coli regulates T lymphocyte migration.Semantic proximity Read ↗

Intestinal immune responses in wild-type and Apcmin/+ mouse, a model for colon cancer.Semantic proximity Read ↗

Intestinal genetic inactivation of caspase-8 diminishes migration of enterocytes.Semantic proximity Read ↗

Leptin induces an Apc genotype-associated colon epithelial cell chemokine production pattern associated with macrophage chemotaxis and activation.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.