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Article

A role of the C-terminus of aquaporin 4 in its membrane expression in cultured astrocytes.

Genes to cells : devoted to molecular & cellular mechanisms - 1 Jul 2002

Nakahama Ken-ichi, Fujioka Atsuko, Nagano Mamoru, Satoh Shinsuke, Furukawa Kei-ichi, Sasaki Hiroshi, Shigeyoshi Yasufumi

Abstract excerpt

BACKGROUND: Aquaporin 4 (AQP4) is a predominant water channel protein in mammalian brains, which is localized in the astrocyte plasma membrane. Membrane targeting of AQP4 is essential to perform its function. The mechanism(s) of membrane targeting is not clear in astrocytes. RESULTS: We investigated the role of the C-terminus of AQP4 (short isoform) in its membrane targeting by an expression study of C-terminal...

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Source

Identifiers

PMID: 12081649
DOI: 10.1046/j.1365-2443.2002.00553.x

Genes

AQP4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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