Article
Segregation analysis of diastolic blood pressure in a large pedigree.
Genetic epidemiology - 1 Jan 1993
Weissbecker K A
Abstract excerpt
Hypertension, a major risk factor for cardiovascular diseases, is thought to be inherited to some extent. However, the nature of its genetic component remains unresolved. In the present study, data from a single large kindred (the HGAR1 pedigree) were used to search for evidence of single gene and multifactorial effects on diastolic blood pressure. Commingling analyses found that a mixture of three distributions...
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