Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Tat HIV-1 primary and tertiary structures critical to immune response against non-homologous variants.

The Journal of biological chemistry - 27 Sept 2002

Opi Sandrine, Péloponèse Jean-Marie, Esquieu Didier, Campbell Grant, de Mareuil Jean, Walburger Anne, Solomiac Murielle, Grégoire Catherine, Bouveret Emmanuelle, Yirrell David L, Loret Erwann P

Abstract excerpt

Clinical studies show that in the absence of anti-retroviral therapy an immune response against the human immunodeficiency virus type 1 (HIV-1), transacting transcriptional activator (Tat) protein correlates with long term non-progression. The purpose of this study is to try to understand what can trigger an effective immune response against Tat. We used five Tat variants from HIV strains identified in different...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to AIDS Vaccines
Share to Enzyme-Linked Immunosorbent Assay

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Epitopes

Share to Gene Products, tat

Share to HIV Antibodies

Share to Protein Structure, Secondary

Share to Rabbits

Share to Transcriptional Activation

Source

Identifiers

PMID: 12080071
DOI: 10.1074/jbc.M204393200

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Tat HIV-1 primary and tertiary structures critical to immune response against non-homologous variants.PMID 12080071Read ↗

Tat mutations in an African cohort that do not prevent transactivation but change its immunogenic properties.Semantic proximity Read ↗

Molecular and Genetic Characterization of Natural HIV-1 Tat Exon-1 Variants from North India and Their Functional ImplicationsSemantic proximity Read ↗

[Analysis of Tat protein characteristics in human immunodeficiency virus type 1 sub-subtype A6 (Retroviridae: Orthoretrovirinae: Lentivirus: Human immunodeficiency virus-1)].Semantic proximity Read ↗

Genetic Characterization of HIV-1 tat Gene from Virologically Controlled Aging Individuals with HIV on Long-Term Antiretroviral Therapy.Semantic proximity Read ↗

Genetic Characterization of HIV-1 tat Gene from Virologically Controlled HIV-infected Older Patients on Long-term Antiretroviral TherapySemantic proximity Read ↗

Transactivation and signaling functions of Tat are not correlated: biological and immunological characterization of HIV-1 subtype-C Tat proteinSemantic proximity Read ↗

Tat-specific cytotoxic T lymphocytes select for SIV escape variants during resolution of primary viraemia.Semantic proximity Read ↗

Sequence Conservation and Antibody Cross‐Recognition of Clade B Human Immunodeficiency Virus (HIV) Type 1 Tat Protein in HIV‐1–Infected Italians, Ugandans, and South AfricansSemantic proximity Read ↗

Reservoir cells no longer detectable after a heterologous SHIV challenge with the synthetic HIV-1 Tat Oyi vaccine.Semantic proximity Read ↗

A second-site mutation that restores replication of a Tat-defective human immunodeficiency virus.Semantic proximity Read ↗

Rapid progressing allele HLA-B35 Px restricted anti-HIV-1 CD8+ T cells recognize vestigial CTL epitopes.Semantic proximity Read ↗

HIV Tat protein: Is Tat-C much trickier than Tat-B?Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.