Article
Resistance to quinupristin-dalfopristin due to mutation of L22 ribosomal protein in Staphylococcus aureus.
Antimicrobial agents and chemotherapy - 1 Jul 2002
Malbruny Brigitte, Canu Annie, Bozdogan Bülent, Fantin Bruno, Zarrouk Virginie, Dutka-Malen Sylvie, Feger Celine, Leclercq Roland
Abstract excerpt
The mechanism of resistance to the streptogramin antibiotics quinupristin and dalfopristin was studied in a Staphylococcus aureus clinical isolate selected under quinupristin-dalfopristin therapy, in four derivatives of S. aureus RN4220 selected in vitro, and in a mutant selected in a model of ra...
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