Article
Characterisation of in vitro-selected mutants of Ureaplasma parvum resistant to macrolides and related antibiotics.
International journal of antimicrobial agents - 1 Feb 2007
Pereyre S, Métifiot M, Cazanave C, Renaudin H, Charron A, Bébéar C, Bébéar C M
Abstract excerpt
Resistant mutants of Ureaplasma parvum were selected by serial passages of a susceptible strain in subinhibitory concentrations of different macrolides and related antibiotics (erythromycin, azithromycin, josamycin, quinupristin, quinupristin/dalfopristin, pristinamycin and telithromycin). Mechanisms of resistance were characterised by sequencing portions of genes encoding 23S rRNA and ribosomal proteins L4 and...
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