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Article

Regulation of transcription of the human prepronociceptin gene by Sp1.

Gene - 15 May 2002

Zaveri Naunihal T, Green Christopher J, Polgar Willma E, Huynh Nhung, Toll Lawrence

Abstract excerpt

Nociceptin/orphanin FQ is a recently discovered neuropeptide and the endogenous ligand for opioid receptor-like-1. The promoter region of the precursor protein prepronociceptin (ppN/OFQ) has been cloned and sequenced. We have previously shown that a stretch of 110 bases immediately 5' to the first intron 23 bp upstream of the ATG start codon is responsible for significant enhancement of transcription of the human...

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PMID: 12062800
DOI: 10.1016/s0378-1119(02)00565-6

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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