Article
Spontaneous reversion of tsBN67 cell proliferation and cytokinesis defects in the absence of HCF-1 function.
Experimental cell research - 1 Jul 2002
Reilly Patrick T, Herr Winship
Abstract excerpt
Mammalian HCF-1 is a highly conserved and abundant chromatin-bound protein that plays a role in both herpes simplex virus (HSV) immediate-early (IE) gene transcription and cell proliferation. Its role in cell proliferation has been evidenced through the analysis of a temperature-sensitive hamster cell line called tsBN67. When placed at nonpermissive temperature, tsBN67 cells undergo a stable and reversible...
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