Article
A genome wide scan for early onset primary hypertension in Scandinavians.
Human molecular genetics - 15 Aug 2003
von Wowern Fredrik, Bengtsson Kristina, Lindgren Cecilia M, Orho-Melander Marju, Fyhrquist Frej, Lindblad Ulf, Råstam Lennart, Forsblom Carol, Kanninen Timo, Almgren Peter, Burri Philippe, Katzman Per, Groop Leif, Hulthén U Lennart, Melander Olle
Abstract excerpt
With the aim of identifying hypertension susceptibility loci, we performed a genome wide scan in Scandinavian sib-pairs with early onset primary hypertension. To be classified as affected, a diagnosis of primary hypertension at age </=50 years was required. Two hundred and forty three patients with onset of primary hypertension at 40.0+/-7.7 (mean+/-SD) years from 91 families (91 sib-ships with a mean of 2.7 and...
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