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Article

Implication of chromosome 18 in hypertension by sibling pair and association analyses: putative involvement of the RKHD2 gene.

Hypertension (Dallas, Tex. : 1979) - 1 Nov 2006

Guzmán Blanca, Cormand Bru, Ribasés Marta, González-Núñez Daniel, Botey Albert, Poch Esteban

Abstract excerpt

This study aims to test the implication of regions on chromosomes 9, 17, and 18 in essential hypertension (EH) by combining sibling-pair linkage analysis and case-control association studies. The selection of these chromosomal regions is based on previous evidence of their implication in EH or in related phenotypes by comparative genomics in several rat models and from genome-wide linkage studies in humans. For...

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Identifiers

PMID: 17015768
DOI: 10.1161/01.HYP.0000244085.52918.a0

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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