Article
Arterial wall thickness and the risk of recurrent ischemic events in carriers of the prothrombin G20210A mutation with clinical manifestations of atherosclerosis.
Atherosclerosis - 1 Jul 2002
Gerdes Victor E A, ten Cate Hugo, de Groot Eric, Kwa Vincent I H, Prins Martin H, Reitsma Pieter H, Büller Harry R, Brandjes Dees P M
Abstract excerpt
The G20210A mutation in the prothrombin gene is an established risk factor for venous thrombosis. There is controversy about the role of this mutation in arterial thrombotic disease and atherosclerosis. We determined the presence of the prothrombin mutation and examined its influence on carotid and femoral artery intima-media thickness (IMT) and the occurrence of new ischemic events during follow-up in 277...
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