Article
The prothrombin 20210A allele and its association with myocardial infarction.
Thrombosis and haemostasis - 1 Jun 1999
Croft S A, Daly M E, Steeds R P, Channer K S, Samani N J, Hampton K K
Abstract excerpt
The relationship between the prothrombin (PT) 20210A allele and arterial disease is controversial. We conducted a case-control study to assess its contribution to risk of myocardial infarction (MI). Five hundred and thirty-nine acute MI patients and 498 control subjects aged <75 years were studied. Two percent of cases carried the PT20210A allele compared to 2.8% of controls. The odds ratio for MI was 0.72 (95%...
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