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Article

Directing Cell Phenotype: Quantitative Single-Cell Migration Assay Leveraging Tunable Extracellular Surfaces.

Langmuir : the ACS journal of surfaces and colloids - 10 Jun 2025

Kaler Logan I, Robitaille Michael C, Christodoulides Joseph A, Calhoun Patrick J, Byers Jeff M, Raphael Marc P

Abstract excerpt

From in vitro cancer research to immunology, single-cell migration assays are among the most common assays for gaining phenotypic insight into the dynamics of adhesion and migration. In general, however, the extracellular environments used in these assays are poorly characterized, which can lead to difficulty interpreting the resulting cellular behavior. Here we introduce a single-cell migration assay which...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 40444653
DOI: 10.1021/acs.langmuir.4c05135
PMCID: PMC12164332

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