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Article

[Effect of products of germ-line and somatic gene mutations on chromatin remodeling].

Casopis lekaru ceskych - 1 Mar 2002

Smardová J, Smarda J

Abstract excerpt

Chromatin remodeling is engaged in basic cell functions as DNA replication, recombination, DNA repair and transcription of genes. Chromatin is remodeled by ATP-dependent chromatin remodeling complexes and protein complexes covalently modifying histones. Germ-line mutations of the genes coding for proteins which participate in chromatin remodeling cause severe developmental diseases and they increase a risk of...

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PMID: 12046254

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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