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A liquid-based method for the assessment of bacterial pathogenicity using the nematode Caenorhabditis elegans.

FEMS microbiology letters - 7 May 2002

Smith Martin P, Laws Thomas R, Atkins Timothy P, Oyston Petra C F, de Pomerai David I, Titball Richard W

Abstract excerpt

Caenorhabditis elegans has previously been used as an alternative to mammalian models of infection with bacterial pathogens. We have developed a liquid-based assay to measure the effect of bacteria on the feeding ability of C. elegans. Using this assay we have shown that Pseudomonas aeruginosa strain PA14, Burkholderia pseudomallei and Yersinia pestis were able to inhibit feeding of C. elegans strain N2. An...

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PMID: 12044672
DOI: 10.1111/j.1574-6968.2002.tb11178.x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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