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Article

Cytokines regulate development of human mast cells from hematopoietic progenitors.

International journal of hematology - 1 May 2002

Nakahata Tatsutoshi, Toru Hano

Abstract excerpt

Combination of stem cell factor (SCF) and interleukin-6 (IL-6) significantly promoted proliferation of human mast cells from cord blood CD34+ cells. Most of the cells, cultured in the presence of SCF and IL-6 for 10 weeks, expressed c-kit and contained a significant amount of histamine and tryptase and a low amount of chymase. Both tryptase-positive chymase-negative mast cells (MC(T)) and tryptase-positive...

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Identifiers

PMID: 12041663
DOI: 10.1007/BF02982123

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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