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Article

Pivotal advance: IgE accelerates in vitro development of mast cells and modifies their phenotype.

Journal of leukocyte biology - 1 Aug 2008

Kashiwakura Jun-ichi, Xiao Wenbin, Kitaura Jiro, Kawakami Yuko, Maeda-Yamamoto Mari, Pfeiffer Janet R, Wilson Bridget S, Blank Ulrich, Kawakami Toshiaki

Abstract excerpt

Antigen-dependent activation of IgE-bound mast cells is critical for immediate hypersensitivity and other allergic disorders. Recent studies have revealed the effects of monomeric IgEs on mast cell survival and activation. Furthermore, IgE molecules exhibit a wide range of heterogeneity in the ab...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 18477690
DOI: 10.1189/jlb.1207841
PMCID: PMC2516357

Genes

TNF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-18477690-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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