Article
Small mutations in Bordetella pertussis are associated with selective sweeps.
PloS one - 1 Jan 2012
van Gent Marjolein, Bart Marieke J, van der Heide Han G J, Heuvelman Kees J, Mooi Frits R
Abstract excerpt
Bordetella pertussis is the causative agent of pertussis, a highly contagious disease of the human respiratory tract. Despite high vaccination coverage, pertussis has resurged and has become one of the most prevalent vaccine-preventable diseases in developed countries. We have proposed that both waning immunity and pathogen adaptation have contributed to the persistence and resurgence of pertussis. Allelic...
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